Contraindicated (1)pentobarbital will decrease the extent or effect of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is responsible for the formation and elimination of cariprazine's Lively metabolites.
pentobarbital will decrease the level or effect of siponimod by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of siponimod with a drug that triggers average CYP2C9 moreover a reasonable or robust CYP3A4 inducer will not be encouraged.
Contraindicated (1)pentobarbital decreases amounts of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can lessen panobinostat ranges by ~70% and bring on therapy failure.
pentobarbital will lower the level or result of fludrocortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will minimize the extent or effect of abiraterone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
lasmiditan, pentobarbital. Either will increase outcomes of another by sedation. Use Warning/Monitor. Coadministration of lasmiditan together with other CNS depressant drugs, like alcohol haven't been evaluated in scientific scientific studies. Lasmiditan may perhaps result in sedation, and other cognitive and/or neuropsychiatric adverse reactions.
pentobarbital will lessen the extent or result of quinidine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will minimize the level or effect of quinine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.
pentobarbital will lessen the extent or impact of tinidazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lower the level or influence of cobimetinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Avoid coadministration. Strong or average CYP3A inducers could reduce cobimetinib systemic exposure by >80% and decrease its efficacy.
Keep an eye on Closely (one)pentobarbital will lower the level or impact of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the extent or influence of tolterodine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Coadministration of zuranolone with other CNS depressants may well enhance impairment of psychomotor efficiency or CNS depressant effects. If click here unavoidable, think about dose reduction. .
pentobarbital will minimize the level or influence of armodafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.